TEST 400
Generic Name: Testosterone ester blend injection (testosterone cypionate + testosterone enanthate + testosterone decanoate)
Strength & Packaging: Based on the formula you provided: 10 mL multidose vial containing 120 mg/mL testosterone cypionate, 120 mg/mL testosterone enanthate, and 160 mg/mL testosterone decanoate for a total of 400 mg/mL. I found official labeling for testosterone cypionate and testosterone enanthate injections, and official testosterone-ester data sheets, rather than a single official insert for a product specifically named TEST 400; accordingly, the entry below is written as a neutral composite monograph.

Description
TEST 400 is a long-acting injectable androgen preparation composed of multiple testosterone esters intended to provide sustained release of testosterone after intramuscular administration. Official testosterone injection labels describe these products as sterile oily intramuscular solutions used for testosterone replacement in appropriately selected patients.

Indications
Testosterone therapy is indicated for testosterone replacement in males with confirmed deficiency or absence of endogenous testosterone, including primary hypogonadism and hypogonadotropic hypogonadism, when supported by clinical findings and laboratory evaluation. Some official testosterone-ester data sheets also note use in androgen-deficiency–associated osteoporosis in certain markets.

Dosage & Administration
Use only under the supervision of a licensed clinician. Testosterone injectable products are administered as deep intramuscular injections, with care taken to avoid intravascular or intravenous administration. Dosing should be individualized according to diagnosis, serum testosterone levels, clinical response, and adverse effects. Official testosterone cypionate labeling includes a labeled dosing range of 50 mg to 400 mg every 2 to 4 weeks, but an exact regimen for a mixed-ester 400 mg/mL product should follow the specific manufacturer’s prescribing information and the prescriber’s judgment.

Mechanism of Action
After intramuscular injection, the ester components are gradually hydrolyzed to release testosterone, which exerts androgenic effects in target tissues. Androgens support the maintenance of male secondary sexual characteristics and have been reported to stimulate red blood cell production; exogenous testosterone also suppresses endogenous gonadotropin signaling through negative feedback on LH and FSH.

Precautions
Testosterone products are contraindicated in men with carcinoma of the breast or known or suspected carcinoma of the prostate, in pregnant women because of fetal virilization risk, and in patients with known hypersensitivity to product ingredients. Important precautions with testosterone therapy include polycythemia, blood-pressure increases, fluid retention, possible interaction with insulin or other glucose-lowering therapy, interaction with warfarin, and higher edema risk when used with corticosteroids, particularly in patients with cardiac, renal, or hepatic disease. Testosterone is also a Schedule III controlled substance, and official labeling warns about abuse and dependence with serious cardiovascular and psychiatric consequences.

Side Effects
Reported adverse reactions with testosterone products include injection-site pain or reaction, gynecomastia, acne, seborrhea, male-pattern hair loss, headache, mood changes or depression, prolonged or frequent erections, and oligospermia, subfertility, or infertility at high doses. Fluid retention and lipid changes may occur, and serious reported events have included myocardial infarction and stroke.

Storage
Store at 20°C to 25°C (68°F to 77°F) under controlled room temperature conditions and protect from light.